Academy of Mathematics and Systems Science, CAS Colloquia & Seminars
Speaker:
Prof. Wing Hung Wong,Member of the US National Academy of Sciences,Stephen R. Pierce Family Goldman Sachs Professor in Science and Human Health,Stanford University
Inviter:
Min Chen
Title:
Statistics and Sequencing Technology
Time & Venue:
2015.6.25 11:00-11:50am 思源楼一层报告厅
Abstract:
In this talk we will discuss the role of statistics in the “primary” and “secondary” analysis of DNA sequencing data. By these we mean the process of turning the raw signals of the sequencing instrument to sequence reads (primary analysis) and the process of aligning and assembling the reads to detect variations from the reference genome (secondary analysis). We will see that statistical ideas have been pivotal in every step in the development of successful analysis methodologies. After presenting examples from previous and current generations of sequencing technologies, we will briefly examine some new statistical challenges posted by emerging (third generation) sequencing technologies.
Appendix：
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