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(2018.7.8)Prof. Hulin Wu:Biological Dynamic Systems: Inverse Problems Based on Experimental Data
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Update time: 2018-07-13
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Academy of Mathematics and Systems Science, CAS
Colloquia & Seminars

Speaker:

Prof. Hulin Wu,University of Texas Health Science Center

Inviter: 洪佳林
Title:
Biological Dynamic Systems: Inverse Problems Based on Experimental Data
Time & Venue:
2018.7.8 16:00-17:00 N222
Abstract:
Differential equation models are widely used to describe and characterize the behaviors of dynamic systems in physics, engineering, finance, economy, biology and among many other scientific fields. The properties and forward problems of various differential equations have been well studied in the past decades. However, the inverse problem (model construction and parameter estimation) of even simplest ordinary differential equation (ODE) models have not been fully explored until recently. In this talk, I will share our experience and results in developing statistical methods for ODE inverse problems via biomedical application examples, in particular modeling immune response to influenza infections. The model construction and parameter estimation methods for linear, nonlinear and high-dimensional ODEs will be introduced. Biological findings based on the established dynamic models will be discussed.
 

 

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